| 摘要 |
The process enables peptides to be synthesized from amino acids with PEG as the polymer support. The PEG support rendered PEG-peptide conjugate soluble in a common organic solvent for solution phase peptide synthesis, thus the process of this invention has the advantage of a solution phase synthesis. The PEG-peptide conjugate can be isolated in a precipitation-filtration-wash sequence by adding a second solvent; thus the process of this invention also has the advantage of a solid phase peptide synthesis. The peptides obtained by this synthesis route are used, in particular, in pharmaceutical applications.
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