CATIONIC STEROL DERIVATIVES, PH-SENSITIVE LIPOSOMES COMPRISING CATIONIC STEROL DERIVATIVES AND METHOD FOR LOADING LIPOSOMES WITH ACTIVE SUBSTANCES

摘要

Disclosed is a sterol derivative having a pKa value of 3.5 - 8 according to the general formula cation - spacer 2 - Y - spacer 1 - X - sterol, wherein Y and X represent bonding groups. The invention also relates to liposomes containing said sterol derivatives.