The present invention provides non-naturally occurring proteins that bind to RANK and polynucleotides encoding the same. The proteins of the invention can be used for enhancing bone formation by either inhibiting bone resorption or inducing osteogenesis.
申请公布号
WO03033663(A2)
申请公布日期
2003.04.24
申请号
WO2002US33022
申请日期
2002.10.15
申请人
BARNES-JEWISH HOSPITAL;LAM, JONATHAN;ROSS, PATRICK, F.;TEITELBAUM, STEVEN, L.
发明人
LAM, JONATHAN;ROSS, PATRICK, F.;TEITELBAUM, STEVEN, L.