Methods of treating antibody-mediated pathologies using agents which inhibit CD21

摘要

Provided herein are methods of treating antibody-mediated pathologies such as autoimmune diseases (e.g., SLE, ITP, and thyroiditis) using agents which inhibit CD21/C3d interaction to ameliorate one or more symptoms of an antibody-mediated pathology. Also provided herein are methods for delaying the development of antibody-mediated pathologies using agents that inhibit CD21/C3d interaction to effect such delay.