MULTIPLEXED ANALYSIS OF POLYMORPHIC LOCI BY CONCURRENT INTERROGATION AND ENZYMEMEDIATED DETECTION

摘要

The invention provides methods and processes for the identification of polymorphisms at one or more designated sites, without interference from non - designated sites located within proximity of such designated sites. Probes a re provided capable of interrogation of such designated sites in order to determine the composition of each such designated site. By the methods of th is invention, one or more mutations within the CFTR gene and the HLA gene compl ex can be identified.