Nucleic acid for regulating the ABCA7 gene, molecules modulating its activity and therapeutic applications

摘要

The present invention relates to nucleic acid sequences that regulate the transcription of the ABCA7 gene, which may be involved in the metabolism of lipids in hematopoietic tissues, as well as in cell signaling mechanisms linked to the immune reaction and to inflammation. The invention also relates to polypeptides and polynucleotides that may be involved in diseases associated with the genetic locus q13 of chromosome 19.