发明名称 |
Tablet comprising a phosphate-binding polymer |
摘要 |
<p>A tablet containing a phosphate-binding polymer, which has an average particle size of 400 mu m or less, contains particles of 500 mu m or less in particle size at a ratio of 90% or more and has a moisture content of 1 to 14%, together with crystalline cellulose and/or low substituted hydroxypropylcellulose, and a process for producing the same are disclosed. <??>The phosphate-binding polymer tablet according to the present invention contains the active component at a high ratio, is excellent in the ability to bind to phosphate and are quickly disintegration in an acidic to a neutral region while being little affected by the stirring strength. Accordingly, it is an excellent preparation capable of regulating changes in bioavailability due to the gastrointestinal motions and pH value.</p> |
申请公布号 |
EP1304104(A2) |
申请公布日期 |
2003.04.23 |
申请号 |
EP20020025683 |
申请日期 |
1998.04.03 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
MATSUDA, KATSUYA;KUBOTA, RYUJI |
分类号 |
A61K9/20;(IPC1-7):A61K9/20;A61K31/785 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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