| 摘要 |
PROBLEM TO BE SOLVED: To provide a high-purity N-monosubstituted piperazine by removing piperazine which is an impurity contained in the N-monosubstituted piperazine. SOLUTION: This method for purifying the N-monosubstituted piperazine is carried out as follows. A mineral acid or an organic acid is added to the N-monosubstituted piperazine represented by the general formula (1) (wherein, R<1> denotes an alkyl group, an aralkyl group or an aromatic substituent) and distillation is then conducted. The high-purity N-monosubstituted piperazine can be obtained by adding 0.1-10% of the mineral acid or organic acid and carrying out simple distillation. |
