发明名称 Diesters or polyesters of naphthalene dicarboxylic acid as solubilizer/stabilizer for retinoids
摘要 A topical composition for skin treatment comprising about 60.001% to 1% by weight of a retinoid solubilizer and/or stabilized with preferably about 0.1% to about 50% by weight of a diester or polyester of a naphthalene dicarboxylic acid having compound formula (I), (II), (III) or mixtures:wherein R1 is an alkyl group, straight chain or branched, having 1 to 22 carbon atoms;wherein each R1, same or different, is an alkyl group having 1 to 22 carbon atoms, a diol having the structure HO-R2-OH, or a polyglycol having the structure HO-R3-(-O-R2-)m-OH wherein R2 and R3, same or different, are each an alkylene group, straight chain or branched, having 1 to 6 carbon atoms, and wherein m and n are each 1 to about 100, or a mixture thereof.
申请公布号 US6551605(B2) 申请公布日期 2003.04.22
申请号 US20010827640 申请日期 2001.04.06
申请人 HAARMANN & REIMER 发明人 BONDA CRAIG A.
分类号 A61K8/37;A61K8/67;A61K9/00;A61K47/14;A61K47/34;A61Q19/00;(IPC1-7):A61K7/42;A61K7/44;A61K31/07;A01N31/04 主分类号 A61K8/37
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