发明名称 Unsymmetrical cyclic diamine compound
摘要 Cyclic diamine compounds of formula (1) are disclosed:whereinA is (CH2)n, (CH2)n-CH=CH, CO-(CH2)n or CO-(CH2)n-CH=CH, in which n is a number of 0 to 3; Z represents a formula (2) or (3):in which R1, R2, R4, R5 and R6 are individually a hydrogen atom, alkyl group, alkoxy group, halogen atom or nitro group; R3is a hydrogen atom, alkyl group, alkoxy group, halogen atom, nitro group, naphthyl group, or phenyl group which may be substituted by 1 to 3 substituents selected from the group consisting of alkyl groups, alkoxy groups, halogen atoms, a nitro group and a phenyl group; and X and Y are individually CH or a nitrogen atom; and m is 1 or 2;an acid-addition salt thereof, or a hydrate thereof, and a medicine containing such a compound.
申请公布号 US6552188(B2) 申请公布日期 2003.04.22
申请号 US20010893699 申请日期 2001.06.29
申请人 KOWA CO., LTD. 发明人 KODAMA TATSUHIKO;TAMURA MASAHIRO;ODA TOSHIAKI;YAMAZAKI YUKIYOSHI;NISHIKAWA MASAHIRO;TAKEMURA SHUNJI;DOI TAKESHI;KYOTANI YOSHINORI
分类号 A61P9/10;A61P11/06;A61P29/00;A61P37/08;A61P43/00;C07D213/36;C07D213/81;C07D213/82;C07D401/12;(IPC1-7):A61K31/496;A61K31/551;C07D241/04;C07D243/08;C07D401/06 主分类号 A61P9/10
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