ANTICANCER AGENT COMPOSITION CONTAINING EXTRACT OF EURYA EMARGINATA

摘要

PURPOSE: An anticancer agent composition containing an organic solvent extract of Eurya emarginata(Thunb.) Makino having an inhibition effect on the proliferation of tumor cells is provided. The composition is low in toxicity and inhibits the growth of cancer cells by inducing apoptosis thereof. CONSTITUTION: Leaves of Eurya emarginata(Thunb.) Makino are ground, soaked in 2 to 20 times of a solvent, agitated at room temperature for 20 to 30hr, filtered and concentrated under reduced pressure. The anticancer agent composition contains the Eurya emarginata extract and a pharmaceutically acceptable salt selected from a diluent, a flavoring, solubilizing agent, a lubricating agent, a binding agent and a disintegrating agent. The solvent is selected from methanol, ethanol, butanol, propanol, hexane, ethyl acetate, acetone, chloroform, methylene chloride and a mixture thereof. The effective daily dose of the extract is 10 to 60mg/kg of body weight.