REMEDIES FOR LIFE STYLE-RELATED DISEASES OR CIBOPHOBIA AND METHOD OF SCREENING THE SAME

摘要

It is intended to provide novel remedies for life style−related diseases or remedies for cibophobia whereby food intake can be preferably controlled and a method of screening the same. More specifically speaking, remedies for life style−related diseases containing as the active ingredient a substance inhibiting the expression or function of clone 901 which is a GPCR expressed in the hypothalamus; remedies for cibophobia containing as the active ingredient a substance potentiating the expression or function of the above clone; a screening system comprising a series of co−expression systems of the clone 901 and various G proteins; and a method of screening a substance having a therapeutic activity on life style−related diseases or cibophobia using the above screening system.