发明名称 |
METHODS FOR REGULATING CO-STIMULATORY MOLECULE EXPRESSION WITH REACTIVE OXYGEN |
摘要 |
The invention is based in part on the discovery that the expression of co- stimulatory molecules such as B7.1, B7.2 or CD40 can be regulated using reactive oxygen species (ROS). Thus, the invention relates to methods of regulating co-stimulatory molecules by modulating reactive oxygen. The metho ds and products are useful, for example, for modulating antigen specific immune responses, treating disease, and for modulating cell growth.
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申请公布号 |
CA2463442(A1) |
申请公布日期 |
2003.04.17 |
申请号 |
CA20022463442 |
申请日期 |
2002.10.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
TRAUGER, RICHARD;NEWELL, EVAN;CAMLEY, ROBERT E.;NEWELL ROGERS, MARTHA KAREN;CHRISTIANSEN, THOMAS;CELINSKI, ZBIGNIEW;ILL, C. RICHARD;VILLALOBOS-MENUEY, ELIZABETH |
分类号 |
A61K31/20;A61K35/12;A61K38/00;C12N5/00;C12N5/08;C12N13/00;(IPC1-7):A61K45/00;A61P25/00;A61P37/00;A61N5/02;A61K38/28;A61K33/40 |
主分类号 |
A61K31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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