Compositions and methods of zearalenone detoxification

摘要

The present invention provides compositions and methods for detoxification of mycotoxins. Compositions include novel nucleotide sequences encoding zearalenone detoxification polypeptides, and biologically active variants thereof. Further provided are methods for mycotoxin detoxification using the sequences disclosed herein. One method comprises stably incorporating into the genome of a plant cell, a nucleotide sequence of the present invention operably linked to a heterologous promoter and regenerating a stably transformed plant that expresses the nucleotide sequence. An additional method comprises incorporating a nucleotide sequence of the present invention operably linked to a heterologous promoter into a microorganism and applying said microorganism to a plant or grain.