发明名称 |
Process for preparing silymarin exhibiting enhanced solubility |
摘要 |
<p>The inventors have devised novel approaches for the preparation of flavanolignan compositions of enhanced solubility and substantially free of toxic contaminants. Such novel approaches are based on spray drying or lyophilizing to dry a diluted preparation of flavanolignan. These approaches avoid the use of toxic excipients and or carriers commonly used to precipitate flavanolignan concentrates and thus address the drawbacks of existing methods and compositions.</p> |
申请公布号 |
CZ20013153(A3) |
申请公布日期 |
2003.04.16 |
申请号 |
CZ20010003153 |
申请日期 |
2001.08.30 |
申请人 |
IVAX PHARMACEUTICALS S.R.O. |
发明人 |
CVAK LADISLAV;STUCHLIK MILAN;BENESOVA KVETOSLAVA |
分类号 |
A61K9/19;A61K9/02;A61K31/79;A61K36/00;A61K36/28;A61K47/10;A61P1/16;A61P3/04;A61P3/10;A61P35/00;A61P39/02;C07D311/40;(IPC1-7):A61K35/78;A61K9/20 |
主分类号 |
A61K9/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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