发明名称 |
QUINOLINONE DERIVATIVES AS TYROSINE KINASE INHIBITORS |
摘要 |
The present invention relates to methods for synthesizing a 4-amino substituted compound of structure I, where the variables have the values described herein. The methods comprise reacting a substituted or unsubstituted ethyl 2-benzimidazolyl-2-acetate with a substituted or unsubstituted 2-aminobenzonitrile and a base or a Lewis acid, whereby the 4-amino substituted compound of structure I is provided.
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申请公布号 |
KR20030029974(A) |
申请公布日期 |
2003.04.16 |
申请号 |
KR20037003558 |
申请日期 |
2003.03.11 |
申请人 |
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发明人 |
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分类号 |
C07D243/08;C07D401/04;A61K31/19;A61K31/4709;A61K31/4745;A61K31/496;A61K31/513;A61K31/5377;A61K31/541;A61K31/551;A61P35/00;A61P43/00;C07D401/14;C07D403/04;C07D405/04;C07D409/04;C07D409/14;C07D413/04;C07D417/04;C07D453/02;C07D471/04;C07D487/08;C07D519/00 |
主分类号 |
C07D243/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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