| 发明名称 |
Compounds and methods for the treatment and prophylaxis of bacterial infection |
| 摘要 |
<p>The invention provides mutant forms of pore-forming toxins. These mutant toxins may be used in vaccines for the prevention of bacterial infection. Additionally, dominant negative mutants may be administered as therapeutics for the treatment of bacterial infection.</p> |
| 申请公布号 |
CZ20023662(A3) |
申请公布日期 |
2003.04.16 |
| 申请号 |
CZ20020003662 |
申请日期 |
2001.05.04 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
COLLIER R. JOHN;SELLMAN BRET R. |
| 分类号 |
A61K39/02;A61K39/00;A61K39/395;A61P31/00;A61P31/04;C07K14/32;C07K16/12;(IPC1-7):C07K14/32;A61K39/07;C12N15/01 |
主分类号 |
A61K39/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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