| 发明名称 |
Methods and means for the use of the adventitial toll-like receptor |
| 摘要 |
<p>The present invention relates to the field of molecular biology and medicine. It particularly relates to methods and means for interfering with the formation of a neointima/scar and/or a plaque. The invention provides a method for interfering with the formation of a neointima/scar and/or a plaque in a blood vessel comprising providing a ligand capable of modulating Toll-like receptor activity of adventitial cells.</p> |
| 申请公布号 |
EP1302206(A1) |
申请公布日期 |
2003.04.16 |
| 申请号 |
EP20010203846 |
申请日期 |
2001.10.11 |
| 申请人 |
UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITEIT UTRECHT |
发明人 |
DE KLEIJN, DOMINICUS PASCHALIS VICTOR;PASTERKAMP, GERARD |
| 分类号 |
A61K38/39;A61K38/02;A61P9/10;A61P19/00;C07K14/705;(IPC1-7):A61K31/739;A61K38/16;G01N33/50;C12N15/00;C07K14/00;A61K48/00;A61K31/715 |
主分类号 |
A61K38/39 |
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