发明名称 NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION
摘要 The invention relates to new derivatives of cyano-aryl (or cyanoheteroaryl)- carbonyl-piperazinyl-pyrimidines (I), wherein R1 represents an OR3 radical, wherein R3 represents a radical deriving from a saturated hydrocarbon with a linear or branched chain of 1 to 4 carbon atoms and R2 represents a phenyl radical substituted at least by a cyano radical (-C.ident.N), or a radical o f a 5 or 6-membered heteroaromatic ring substituted by at least one cyano radical (-C.ident.N). The physiologically acceptable salts of said derivativ es can be used in human and/or veterinary therapeutic applications as sedatives , anticonvulsivants, hypnotics and general anesthetics.
申请公布号 CA2426097(A1) 申请公布日期 2003.04.16
申请号 CA20012426097 申请日期 2001.10.10
申请人 LABORATORIES DEL DR. EDSTEVE, S.A. 发明人 VANO-DOMENECH, DAVID;CORBERA-ARJONA, JORDI;MESQUIDA-ESTEVEZ, MARIA NEUS;FRIGOLA-CONSTANSA, JORDI
分类号 C07D239/47;A61K31/505;A61K31/506;A61P9/10;A61P11/14;A61P21/02;A61P23/00;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/24;A61P25/28;C07D213/00;C07D239/00;C07D239/46;C07D295/00;C07D333/00;C07D401/12;C07D405/12;C07D409/12;(IPC1-7):C07D239/46;C07D403/12 主分类号 C07D239/47
代理机构 代理人
主权项
地址