发明名称 |
Sulfonamide derivative as a matrix metalloproteinase inhibitor |
摘要 |
The present invention provides a novel sulfonamide derivative of general formula (I) useful as an inhibitor of matrix metalloproteinase (MMP), its isomers, pharmaceutically acceptable salts thereof and a process for preparing the same. Since the sulfonamide derivatives of the present invention selectively inhibit MMP activity in vitro, the MMP inhibitors comprising the sulfonamide derivatives as an effective ingredient can be practically applied for the prevention and treatment of all sorts of diseases caused by overexpression and overactivation of MMP.
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申请公布号 |
US6548667(B2) |
申请公布日期 |
2003.04.15 |
申请号 |
US20010018507 |
申请日期 |
2001.12.06 |
申请人 |
SAMSUNG ELECTRONICS CO. LTD. |
发明人 |
PARK YOUNG-JUN;BAE HAE-YOUNG;YOO JI-UK;CHAE MYEONG-YUN;PAEK SANG-HYUN;MIN HYE-KYUNG;PARK HYUN-GYU;RYU CHOON-HO;KIM KYUNG-CHUL;LEE JEOUNG-WOOK |
分类号 |
A61K31/423;A61K31/428;A61K31/4439;A61K31/4523;A61K31/4725;A61K31/5377;A61K31/541;A61K31/662;A61P1/02;A61P9/10;A61P11/00;A61P13/12;A61P19/00;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P35/00;A61P37/00;C07D263/58;C07D277/74;C07D413/12;C07D417/12;C07F9/6541;(IPC1-7):C07D277/68 |
主分类号 |
A61K31/423 |
代理机构 |
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