发明名称 |
Gene encoding for a transmembrane protein |
摘要 |
A gene for a novel transmembrane protein was isolated and its nucleotide sequence was determined. A protein encoded by this gene (TRPC7) has 7 transmembrane regions, and because there is homology with TRP (transient receptor potential), this protein is considered to have calcium channel functions. Further, since a mutation in the TRPC7 gene is frequently observed in patients with manic-depressives insanity, TRPC7 is considered to be a pathogenic gene for bipolar affective disorder.
|
申请公布号 |
US6548272(B1) |
申请公布日期 |
2003.04.15 |
申请号 |
US20000600087 |
申请日期 |
2000.07.11 |
申请人 |
EIKEN KAGAKU KABUSHIKI KAISYA |
发明人 |
SHIMIZU NOBUYOSHI;NAGAMINE KENTARO |
分类号 |
A61K38/00;A61K48/00;C07K14/705;C12N15/12;(IPC1-7):C12N15/12;C12N5/10;C12N15/63 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|