发明名称 NON-NUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE AND A PHARMACEUTICAL COMPOSITION BASED THEREON
摘要 Provided are compounds of general formula (I), wherein R2 is selected from the group consisting of H, F, Cl, (Ñ1-4) alkyl, (C3-4)cycloalkyl and ÑF3; R4 is H or Me; R5 is H, Me or Et, with the proviso that R4 and R5 are not both Me, and if R4 is Me then R5 cannot be Et; R11 is Et, cyclopropyl, propyl, isopropyl, or isobutyl; and Q is selected from the group consisting of (II), (III), (IV) and (V); and pharmaceutically acceptable salts thereof, as inhibitors of HIV reverse transcriptase, wild-type and several mutant strains. (I) (II), (III), (IV), 3 (V)
申请公布号 UA74834(C2) 申请公布日期 2003.04.15
申请号 UA20030010387 申请日期 2001.06.14
申请人 BYORINGER INHELHEIM (CANADA) LTD. 发明人
分类号 A61K31/551;A61K;A61K31/55;A61P31/18;A61P43/00;C07D;C07D471/14;(IPC1-7):C07D471/14;C07D243:00;C07D221:00 主分类号 A61K31/551
代理机构 代理人
主权项
地址