The present invention provides a process from preparing isocoumarin-3-yl derivatives comprising reacting a homophthalic anhydride derivative with a carbonyl compound, wherein the carbonyl group is substituted with an acyl activating group, in the presence of a reaction medium comprising a solvent and a base. The invention also encompasses a process for the preparation of homophthalate esters useful in the preparation of homophthalic anhydride reactants as well as an integrated process wherein the twp reactions are carried out sequentially to afford the desired isocoumarin derivative.
申请公布号
WO03004486(A3)
申请公布日期
2003.04.10
申请号
WO2002US21264
申请日期
2002.07.03
申请人
ILEX PRODUCTS, INC.;BAUTA, WILLIAM, E.;CANTRELL, WILLIAM, R., JR.;LOVETT, DENNIS, P.
发明人
BAUTA, WILLIAM, E.;CANTRELL, WILLIAM, R., JR.;LOVETT, DENNIS, P.