| 摘要 |
The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O2<->) scavenger, their preparation and their use in the treatment of conditions associated with oxidative stress or endothelial dysfunction. In particular, the present invention relates to chemical compounds of formula (I) wherein: R<1 >may be the same or different and are independently selected from hydrogen, alkoyl, alkoxy, carboxy, hydroxy, amino, amido, cyano, nitro, thio, sulphonyl, sulphoxide alkyl groups comprising an NO-donor, provided that at least one R<1 >is a group comprising an NO-donor, R<2 >may be the same or different and are independently selected from alkyl groups; n is an integer 1, 2 or 3; or a salt thereof.
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