发明名称 |
ANTISENSE MODULATION OF SPHINGOSINE-1-PHOSPHATE LYASE EXPRESSION |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of sphingosine-l-phosphate lyase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sphingosine-l-phosphate lyase. Methods of using these compounds for modulation of sphingosine-1-phosphate lyase expression and for treatment of diseases associated with expression of sphingosine-l-phosphate lyase are provided. |
申请公布号 |
WO03028637(A2) |
申请公布日期 |
2003.04.10 |
申请号 |
WO2002US30575 |
申请日期 |
2002.09.26 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT, FRANK, C.;FREIER, SUSAN, M. |
分类号 |
A61K38/00;C12N5/02;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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