| 摘要 |
<p>The invention concerns a method for diagnosing chronic inflammatory bowel diseases (Crohn's disease, ulcerative colitis), and their early diagnosis, their differential diagnosis, assessing the degree of severity, the control and prognosis of their development, along with the treatment. Said method consists in determining the presence and/or the amount of one or several antibodies, which are bound to the ribosomal proteins, in particular P0 and L5, in the serum, in the plasma, in bioptic samples and/or in the stool of a patient suffering from a chronic inflammatory bowel disease, or in a person who is suspected to be affected by such a disease. The inactivation or elimination of such antibodies and/or the effect on the antigen-presenting cells or on T-cells, which specifically react to ribosomal proteins such as P0 and L5, obtained by means of appropriate agents can be used in therapy.</p> |
