COMPOUND WK-5344A AND COMPOUND WK- 5344B, METHOD FOR THEIR OBTAINING AND THEIR PRODUCING STRAIN OF STREPTOMYCES SP

摘要

FIELD: medicine, biology. SUBSTANCE: compounds WK-5344A and WK-5344B are of inhibiting action in relation to cholesterol ester-carrying protein. The method deals with growing Streptomyces sp. WK-5344 FERM BP-6668 strain, moreover, compound WK-5344A and compound WK-5344B are accumulated in medium; then compound WK-5344A and compound WK-5344B should be isolated. The innovation enables to obtain substances efficient for prophylaxis and treatment of diseases caused by cholesterol accumulation in human body. EFFECT: higher efficiency. 4 cl, 8 dwg, 1 tbl