| 摘要 |
The Crystal Nucleating Chip is suitable for use as a high-throughput, low cost, disposable mono-layer array type device, specifically for simultaneously forming crystals of inorganic or organic solute under the inducement of an array of unique SAM's chemical functional head groups and determining their effects on crystal polymorphism and crystal habit of the solute in solutions. The array is a substrate divided into a pattern of pads that directly or indirectly support a number of test compounds each with a specific structure and functionality. A method of using the invention involves bringing the array into contact with a solution in order to promote potential crystallization of the solute. The method further allows for qualitatively determining polymorphism, i.e., crystal formation, and crystal habit of the specific test compounds, e.g. SAMs, through a variety of spectroscopic and microscopic techniques.
|
