发明名称 ANTISENSE MODULATION OF IL-1 RECEPTOR-ASSOCIATED KINASE-4 EXPRESSION
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of IL-1 receptor-associated kinase-4. The compositions comprise antisense compounds, particularly antisense obligonucleotides, targeted to nucleic acids encoding IL-1 receptor-associated kinase-4. Methods of using these compounds for modulation of IL-1 receptor-associated kinase-4 expression and for treatment of diseases associated with expression of IL-1 receptor-associated kinase-4 are provided.
申请公布号 WO03028636(A2) 申请公布日期 2003.04.10
申请号 WO2002US30574 申请日期 2002.09.26
申请人 ISIS PHARMACEUTICALS, INC. 发明人 BENNETT, FRANK, C.;FREIER, SUSAN, M.
分类号 A61K38/00;A61K48/00;C07H21/04;C12N5/02;C12N15/113;C12N15/85 主分类号 A61K38/00
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