GENE REGULATORY PEPTIDES

摘要

The invention relates to the modulation of gene expression in a cell, also called gene control, in particular in relation to the treatment of a variety of diseases. The invention provides a method for modulating expression of a gene in a cell comprising providing said cell with a signalling molecule comprising a peptide or functional analogue thereof. Furthermore, the invention provides a method for identifying or obtaining a signalling molecu le comprising a peptide or functional derivative or analogue thereof capable of modulating expression of a gene in a cell comprising providing said cell wit h a peptide or derivative or analogue thereof and determining the activity and/or nuclear translocation of a gene transcription factor.