发明名称 Pharmaceutical compositions of drug-oligomer conjugates and methods of treating diseases therewith
摘要 Pharmaceutical compositions that include a drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating diseases in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.
申请公布号 US2003069170(A1) 申请公布日期 2003.04.10
申请号 US20020235284 申请日期 2002.09.05
申请人 SOLTERO RICHARD;EKWURIBE NNOCHIRI N.;OPAWALE FOYEKE;REHLANDER BRUCE;HICKEY ANTHONY;LI LI BOVET 发明人 SOLTERO RICHARD;EKWURIBE NNOCHIRI N.;OPAWALE FOYEKE;REHLANDER BRUCE;HICKEY ANTHONY;LI LI BOVET
分类号 A61K47/48;(IPC1-7):A61K38/23;A61K31/56;A61K31/202;A61K38/00 主分类号 A61K47/48
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