N-(4-(4-METHYLTHIAZOL-5-YL) PYRIMIDIN-2-YL) -N-PHENYLAMINES AS ANTIPROLIFERATIVE COMPOUNDS
摘要
The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.
申请公布号
WO03029248(A1)
申请公布日期
2003.04.10
申请号
WO2002GB04383
申请日期
2002.09.27
申请人
CYCLACEL LIMITED;WANG, SHUDONG;MEADES, CHRISTOPHER;WOOD, GAVIN;OSNOWSKI, ANDREW;FISCHER, PETER, MARTIN
发明人
WANG, SHUDONG;MEADES, CHRISTOPHER;WOOD, GAVIN;OSNOWSKI, ANDREW;FISCHER, PETER, MARTIN