摘要 |
The present invention provides methods and compositions for the prophylactic, targeted prophylactic, acute or acutely targeted, or subacute treatment of migraine. Representative methods include an embodiment where a patient is regularly given a therapeutically effective amount of a cyclooxygenase-2 inhibitor, an embodiment where a patient is co-administered a therapeutically effective amount of a combination of a cyclooxygenase-2 inhibitor and acetylsalicylic acid and an embodiment where a patient is co-administered a therapeutically effective amount of a combination of a cyclooxygenase-2 inhibitor and a 5-HT agonist. Representative compositions include cyclooxygenase-2 inhibitors, HT-5 agonists, acetylsalicylic acid and combinations thereof. |