发明名称 4[PIPERIDIN-4-YLIDEN-(3-CARBAMOYLPHENYL)METHYL] BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, SPINAL INJURIES OR GASTROINTESTINAL DISORDERS
摘要 <p>Compounds of general formula (I) wherein R1 is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl and triazolyl; where each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C¿1?-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on thephenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, inparticular in the management of pain.</p>
申请公布号 WO2003029215(A1) 申请公布日期 2003.04.10
申请号 SE2002001804 申请日期 2002.10.02
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