NICARDIPINE HYDROCHLORIDE-CONTAINING AQUEOUS PREPARATION FOR INJECTION

摘要

PROBLEM TO BE SOLVED: To obtain a stabilized aqueous preparation of nicardipine hydrochloride by adding phsphoric acid in an amount of 2-6% based on the nicardipine hydrochloride in no use of polysaccharide. SOLUTION: This nicardipine hydrochloride-containing aqueous preparation is stabilized to the damage of the nicardipine hydrochloride caused by (partial) crystallization or decomposition of the solution by adding a very small amount of phosphoric acid instead of polysaccharide.