| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for using a compound that inhibits wax ester synthesis, and cholesteryl ester synthesis, to inhibit sebum production in patients, thereby treating a sebaceous gland disorder by the overproduction of sebum. SOLUTION: A method of inhibiting sebum production and treating sebaceous gland disorders comprises administering to a patient for a treatment an effective amount of the compound that inhibits acyl-coenzyme A: cholesteryl acyltransferase (ACAT) and acyl-coenzyme A: fatty alcohol acyltransferase (AFAT), provided that the compound is [(2,4,6-triisopropyl-phenyl)-acetyl]- sulfamic acid 2,6-diisopropylphenyl ester or a pharmaceutically acceptable salt or solvate thereof.
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