ARANIDIPINE-CONTAINING COMPOSITION STABLE TO LIGHT

摘要

PROBLEM TO BE SOLVED: To provide a light-stable drug preparation free from the defect of aranidipine easily decompositing with light and with time. SOLUTION: Aranidipine in a drug preparation is stabilized by adding titanium oxide and yellow iron sesquioxide. The amount of titanium oxide is 131.1 pts.wt. based on the aranidipine and that of the yellow iron sesquioxide is 10.0 pts.wt. based on the active substance. The decrease of drug in the drug preparation with light can be prevented by the method to improve the light stability of the preparation.