摘要 |
<p>A subject of the invention, in all possible isomer forms as well as their mixtures, is the compounds of formula (I): in which either R<SUB>1</SUB>: H or CH<SUB>3 </SUB>and R<SUB>2</SUB>: cyclohexyl substituted by an amine, a (CH<SUB>2</SUB>)b-C≡N radical or R<SUB>1 </SUB>and R<SUB>2 </SUB>together with the nitrogen which carries them form a ring with 3, 4 or 5 carbons optionally substituted by an amine R<SUB>3</SUB>: hydrogen, methyl or hydroxyl R<SUB>4</SUB>: hydrogen or hydroxyl R: represents a linear, branched or cyclic chain T: hydrogen, methyl, CH<SUB>2</SUB>CONH<SUB>2</SUB>, CH<SUB>2</SUB>C≡N, a (CH<SUB>2</SUB>)<SUB>2</SUB>NH<SUB>2 </SUB>or (CH<SUB>2</SUB>)<SUB>2</SUB>Nalk<SUP>+</SUP>X<SUP>-</SUP> radical, X halogen and alk alkyl Y: hydrogen, hydroxyl, halogen or OSO<SUB>3</SUB>H, W: H or OH, Z: H, CH<SUB>3</SUB>. The compounds of formula (I) have antifungal properties.</p> |