发明名称 Tumor necrosis factor alpha (TNF-alpha) inhibiting pharmaceuticals
摘要 Pharmaceutical compositions are described for preventing TNF toxicity, comprising as active ingredient the stereospecific (+) enantiomer, having (3S,4S) configuration of DELTA6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to elevated levels of TNF, including septic shock, cachexia and trauma. They are also effective in the treatment of certain chronic degenerative diseases characterized by TNF production, including autoimmune diseases such as AIDS.
申请公布号 US6545041(B2) 申请公布日期 2003.04.08
申请号 US20010971821 申请日期 2001.10.04
申请人 YESSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM 发明人 SHOHAMI ESTHER;GALLILY RUTH;MECHOULAM RAPHAEL
分类号 A61K31/00;A61K31/085;A61K31/22;A61K31/222;A61K31/352;A61P29/00;A61P37/00;A61P37/06;A61P43/00;(IPC1-7):A61K31/35 主分类号 A61K31/00
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