发明名称 1-phenyl-4-(1-[2-aryl]cyclopropyl) methylpiperazines: dopamine receptor ligands
摘要 Disclosed are compounds of the formula:or pharmaceutically acceptable addition salts thereof wherein:R1, R2, R3 R4 and R5, R6, R7, and R8 represent organic and/or inorganic substituents as defined herein,which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behavior, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents.
申请公布号 US6544996(B2) 申请公布日期 2003.04.08
申请号 US20010942369 申请日期 2001.08.29
申请人 NEUROGEN CORPORATION 发明人 ZHANG XIAOYAN;TRAN JENNIFER;ZHAO HE;THURKAUF ANDREW
分类号 A61K31/495;A61P25/18;C07D295/073;C07D295/135;(IPC1-7):A61K31/495;C07D295/33 主分类号 A61K31/495
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