| 发明名称 |
ANTISENSE OLIGONUCLEOTIDE SEQUENCES AS INHIBITORS OF MICROORGANISMS |
| 摘要 |
The invention relates to antisense oligonucleotides which modulate the expression of the ribonucleotide reductase or the secA genes in microorganisms. This invention is also related to methods of using such oligonucleotides in inhibiting the growth of microorganisms. These antisense oligonucleotides are particularly useful in treating pathological conditions in mammals which are mediated by the growth of microorganisms.
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| 申请公布号 |
CA2294305(C) |
申请公布日期 |
2003.04.08 |
| 申请号 |
CA19982294305 |
申请日期 |
1998.07.10 |
| 申请人 |
GENESENSE TECHNOLOGIES INC. |
发明人 |
WRIGHT, JIM A.;YOUNG, AIPING H.;DUGOURD, DOMINIQUE |
| 分类号 |
C12N15/09;A61K31/04;A61K31/12;A61K31/7088;A61K31/711;A61K38/00;C12N15/113;C12Q1/68;(IPC1-7):C12N15/11;C12N15/31 |
主分类号 |
C12N15/09 |
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