| 发明名称 |
Farnesyl Protein transferase inhibitors with in vivo radiosensitizing properties |
| 摘要 |
The present invention is concerned with the finding that farnesyl protein transferase inhibitors have radiosensitizing properties which makes them useful for preparing a pharmaceutical composition for administration before, during or after irradiation of a tumor for treating cancer in vivo.
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| 申请公布号 |
US6545020(B1) |
申请公布日期 |
2003.04.08 |
| 申请号 |
US20010743130 |
申请日期 |
2001.01.03 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
VAN GINCKEL ROBERT FRANCISCUS;FLOREN WIM JOANNA;END DAVID WILLIAM;WOUTERS WALTER BOUDEWIJIN LEOPOLD |
| 分类号 |
C07D401/06;A61K31/4709;A61K41/00;A61P35/00;A61P43/00;C07D401/14;C07D405/14;C07D413/14;(IPC1-7):A61K31/47 |
主分类号 |
C07D401/06 |
| 代理机构 |
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