| 发明名称 |
ANTISENSE OLIGONUCLEOTIDES AND METHODS TO INDUCE TUMOR CELL DEATH |
| 摘要 |
This invention relates to the inhibition and down-regulation of survivin expression. The invention provides methods and antisense oligonucleotides fo r inhibiting or down-regulating survivin expression in cells and promoting apoptosis and cell necrosis.
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| 申请公布号 |
CA2461477(A1) |
申请公布日期 |
2003.04.03 |
| 申请号 |
CA20022461477 |
申请日期 |
2002.09.24 |
| 申请人 |
HYBRIDON, INC. |
发明人 |
SHAFIT-ZAGARDO, BRIDGET;AGRAWAL, SUDHIR;SHANKAR, SAI LATHA;KANDIMALLA, EKAMBAR M.;MANI, SRIDHAR |
| 分类号 |
C12N15/09;A61K31/7125;A61K38/00;C12N5/02;C12N15/113;(IPC1-7):C07H21/04;A61K48/00;C12N15/00 |
主分类号 |
C12N15/09 |
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