| 摘要 |
The invention features a method for the treatment or prevention of mucositis in an individual undergoing or preparing to undergo cancer treatment. The method includes administering a therapeutically effective amount of an inhibitor of NF-kappaB to an individual undergoing or preparing to undergo a treatment for cancer. In certain embodiments, the inhibitor is a compound having the formula: where R1 and R4 are OH, and R2 and R3 are independently OH or H, provided that when R1 and R2 are both OH, R1 and R2 cannot be disposed ortho to one another, and when R3 and R4 are both OH, R3 and R4 cannot be disposed ortho to one another. The compounds of formula I may be cis or trans.
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