Artificial lung of membrane type

摘要

A membrane artificial lung for performing gas exchange between blood and a gas via the membrane by flowing the blood in one side of the membrane and flowing oxygen or an oxygen-containing gas in the other side of the membrane, wherein said membrane comprises a hollow fiber membrane, said hollow fiber membrane comprising poly-4-methylpentene-1 and having an oxygen permeation rate Q(O2) at 25° C. of from 1x10-6 to 3x10-3 (cm3(STP)/cm2.sec.cmHg) and an ethanol flux of from 0.1 to 100 ml/min.m2, wherein said membrane has, in the side of the blood flow, a surface comprising an ionic complex derived from: quaternary aliphatic alkylammonium salts; and heparin or a heparin derivative, and wherein said quaternary alkylammonium salts comprise a quaternary aliphatic alkylammonium salt having from 22 to 26 carbon atoms in total and a quaternary aliphatic alkylammonium salt having from 37 to 40 carbon atoms in total.