METHODS FOR IDENTIFYING AND PURIFYING SMOOTH MUSCLE PROGENITOR CELLS
摘要
The present invention relates to purified smooth muscle progenitor cells and a method for isolating such cells. The purified smooth muscle progenitor cells of the present invention are capable of being induced into the smooth muscle cell lineage at high efficacy (i.e. greater than 60% conversion). The method comprises the steps of transforming cell populations that contain totipotent or pluripotent cells with DNA constructs that are expressed only in the smooth muscle cell lineage, inducing a portion of those cells and identifying those cells that express the construct only after the cells are induced.
申请公布号
WO02074925(A3)
申请公布日期
2003.04.03
申请号
WO2002US08402
申请日期
2002.03.19
申请人
UNIVERSITY OF VIRGINIAN PATENT FOUNDATION;OWENS, GARY, K.;MANABE, ICHIRO