TAILOR-MADE MULTIFUNCTIONAL STEM CELLS AND UTILIZATION THEREOF

摘要

It is intended to provide cells, tissues and organs each capable of serving as a donor for treating diseases without inducing immunorejection, starting wit h no egg cell. This object is achieved by providing multifunctional stem cells having a desired genome. These cells are obtained by treating with a reprogramming factor, constructing fused cells of MHC-lacking stem cells wit h somatic cells, and, after the construction of the fused cells of the stem cells with the somatic cells, eliminating the stem cell-origin genome by a genetic engineering technique, for example, treating with a retrovirus.