发明名称 LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
摘要 The present application describes lactam-containing compounds and derivative s thereof of Formula I: P4-P-M-M4 or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compound s of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
申请公布号 CA2461202(A1) 申请公布日期 2003.04.03
申请号 CA20022461202 申请日期 2002.09.17
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 QUAN, MIMI;ORWAT, MICHAEL;LI, YUN-LONG;HAN, WEI;QIAO, JENNIFER;KOCH, STEPHANIE;LAM, PATRICK;PINTO, DONALD
分类号 C07D401/10;A61K31/437;A61K31/4439;A61K31/444;A61K31/4545;A61K31/506;A61K31/517;A61K31/55;A61K31/553;A61P7/02;A61P9/00;C07D401/12;C07D401/14;C07D413/14;C07D471/04;C07D471/16 主分类号 C07D401/10
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