| 发明名称 |
SPHINGOLIPIDS |
| 摘要 |
The invention relates to compounds of the general formula (I), as defined, a nd to pharmaceutical compositions containing them. The compounds of formula (I) are inhibitors of various lipid-related enzymes. They can be used in reducin g accumulation of sphingolipids and thus in the treatment of lipid storage diseases. The compounds of formula (I) can also be used for the treatment of cancerous diseases and for killing of wild type and drug-resistant cancer cells.
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| 申请公布号 |
CA2461801(A1) |
申请公布日期 |
2003.04.03 |
| 申请号 |
CA20012461801 |
申请日期 |
2001.09.26 |
| 申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALE M</ |
发明人 |
GATT, SHIMON;DAGAN, ARIEH |
| 分类号 |
A61K31/685;A61K31/137;A61K31/167;A61P3/06;A61P31/04;A61P31/10;A61P31/12;A61P33/02;A61P33/06;A61P33/14;A61P35/00;A61P43/00;C07C215/10;C07C215/14;C07C215/24;C07C215/30;C07C215/36;C07C215/68;C07C233/36;C07C233/43;C07C271/16;C07C271/20;C07C271/22;C07C311/04;C07F9/09;C07F9/10;C07F9/113;(IPC1-7):C07C215/68;A61K31/135;A61K31/165;C07C215/28;A61K31/66 |
主分类号 |
A61K31/685 |
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