| 摘要 |
PROBLEM TO BE SOLVED: To provide a suppository that has excellent heat resistance and good drug releasability with the melting and disintegration time shortened at the application site, because the conventional suppository produced by using an oily base material through the melting method is unsatisfactory in heat resistance and requires a longer time for its melting and disintegration to delay the exhibition of effect of a drug. SOLUTION: A mixture of an oily base material, a drug, sucrose and water is mixed at a temperature higher than the melting point of the oily base material and the resultant paste is dried, pulverized and compressed to produce the objective suppository.
|
